IMMUNOME™ v4 Discovery Array

IMMUNOME™ v4 Discovery Array is a protein array which utilises the patented Sengenics KREX™ functional proteomics technology. All proteins on the IMMUNOME™ v4 Discovery Array are correctly folded and functional as they are expressed as fusion proteins with biotin carboxyl carrier protein (BCCP) which acts as a folding marker and solubility enhancer. The IMMUNOME™ v4 Discovery Array contains 1600+ full-length human proteins from biologically significant protein families including kinases, signalling molecules, cytokines, interleukins, chemokines and cancer antigens. The arrays are coated with a proprietary surface which preserves protein folding and inhibits binding of non-specific proteins.

1. Discovery of autoantibody biomarkers for diagnostics

2. Discovery of autoantibody biomarkers of risk of adverse drug reactions

3. Discovery of autoantibody-based therapeutic and prophylactic biologics

4. Selectivity screens for new chemical entities and new biologics

5. Functional assays for any protein and any interacting biomolecule