List of Patents

We are actively seeking opportunities for in-licensing of complementary technologies and out-licensing of Sengenics biomarker patents. Please contact us to arrange a discussion.

KREX™, IMMUNOME™,  SYMPHONI™ and OncoREX™ are registered trademarks of Sengenics and is protected by one or more of the following Patents:


1JP4377242 Methods of determining method, and a folded state to increase the protein tag, and solubility including biotinylation domainView Patent
2AU2002352355 Protein arrays for allelic variants and uses thereofView Patent
3CA2469403 Protein arrays for allelic variants and uses thereofView Patent
4EP1456668Protein arrays for allelic variants and uses thereofView Patent
5AU2003238441 Protein tag comprising a biotinylation domain and method for increasing solubility and determining folding stateView Patent
6CA2474457Protein tag comprising a biotinylation domain and method for increasing solubility and determining folding stateView Patent
7EP1470229Protein tag comprising a biotinylation domain and method for increasing solubility and determining folding stateView Patent
8GB2361698Modification of DNA moleculesView Patent
9EP1485411Arrays of cytosolic accessory proteins immobilized on a surface and pertinent methodsView Patent
10US8999897Protein tag comprising a biotinylation domain and method for increasing solubility and determining folding stateView Patent
11JP4730804Generating protein arraysView Patent
12JP4781628Protein arrays and their use for the allelic variantsView Patent
13US7816098Methods of making and using a protein arrayView Patent
14US20180305840Protein arrays and their use to assay the protein products of highly homologous or related DNA coding sequencesView Patent


1US20180321244A1Method for detection and diagnosis of Oral Cancer in a sampleView Patent
2AU2018100578A4Method for detection and diagnosis of Oral Cancer in a sampleView Patent
310201811119XDetection of biomarkers for Non-Small Cell Lung CancerN/A
410201908922UIdentification of health status in the elderly using immunological biomarkersN/A


1N/ABiomarkers for predicting immunogenicity and therapeutic responses to adalimumab in rheumatoid arthritis patientsN/A

FEATURED PRODUCTS

IMMUNOME
Protein Array

High-throughput
sero-profiling platform

CTA
Protein Array

Screening of
cancer-testis antigens

OncoREX p53
Cancer Array

Cancer drug
screening and discovery

Custom
Protein Array

Flexible format for
high-throughput screening

Sengenics - Functional Proteomics | Krex Technology | Protein Array Supplier

Sengenics is a functional proteomics company that leverages its patented KREX technology for production of full-length, correctly folded and functional proteins. The key application of KREX is the discovery of autoantibody biomarkers for two core medical use cases:  stratification of patients undergoing treatment with autoimmune or cancer drugs and identification of autoantibody biomarkers that may be used to diagnose cancer, autoimmune or neurodegenerative conditions. Some autoantibodies that are identified as diagnostic biomarkers may be protective and have potential in themselves as therapeutic biomolecules.

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