Partnering

Sengenics believes that forging strong external alliances is an essential part of our strategy to access great science. Sengenics is pursuing potential collaborators for early stage opportunities in order to identify and develop innovative products in the following areas of interest:

  1. Discovery of autoantibodies that can stratify drug response
    • Companion diagnostics for early and late stage clinical trials for cancer immunotherapy and autoimmune disease drugs
    • Companion diagnostics for drugs that are already on the market that have to be used by every patient
  2. Autoantibodies related to cancer, autoimmune diseases and Parkinson’s
    • Discovery of autoantibodies that can be diagnostic biomarkers
    • Discovery of autoantibodies that have therapeutic potential
  3. Customised applications leveraging the KREX technology
    • Custom viral and bacterial KREX-based arrays to screen new vaccines
    • Custom viral and bacterial KREX-based arrays for screening individuals for quantitative immune protectivity status prior to vaccine clinical trials

The KREX technology (KREX) or discoveries using KREX can be licensed. Sengenics also has a royalty model depending on specific scenarios as shown below:

KREX technology license (iTAP)

Full technology transfer of KREX. Sengenics grants a site-specific, restricted use, royalty bearing license to KREX-related patents. In addition, full training and on-site support is provided.

Biomarker IP license and Royalties

Sengenics has more than a dozen signed collaboration agreements for a variety of mass market addressable conditions such as Lung Cancer, Zika, Autism, Ageing, Transplantation Rejection and Prostate Cancer.

Royalties on companion diagnostics

Sengenics has a number of collaborations with top pharma and academic institutions in which patients from clinical drug trials have been stratified into responders and non-responders. The 2 main classes of drugs that have been addressed are cancer immunotherapy immune checkpoint inhibitors and drugs for autoimmune diseases.

BUSINESS DEVELOPMENT

We’d love to hear more about your work and perspective. Let’s start a conversation by filling up the form below:


FEATURED PRODUCTS

IMMUNOME
Protein Array

High-throughput
sero-profiling platform

CTA
Protein Array

Screening of
cancer-testis antigens

OncoREX p53
Cancer Array

Cancer drug
screening and discovery

Custom
Protein Array

Flexible format for
high-throughput screening

Sengenics - Functional Proteomics | Krex Technology | Protein Array Supplier

Sengenics is a functional proteomics company that leverages its patented KREX technology for production of full-length, correctly folded and functional proteins. The key application of KREX is the discovery of autoantibody biomarkers for two core medical use cases:  stratification of patients undergoing treatment with autoimmune or cancer drugs and identification of autoantibody biomarkers that may be used to diagnose cancer, autoimmune or neurodegenerative conditions. Some autoantibodies that are identified as diagnostic biomarkers may be protective and have potential in themselves as therapeutic biomolecules.

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